CARDURA 1MG TAB 20S

CARDURA 1 mg Tablets (20 Tablets)
Active Ingredient: Doxazosin Mesylate 1 mg
Therapeutic Class:

• Alpha-1 Adrenergic Receptor Blocker
  Dosage Form: Oral Tablet

Indications:

CARDURA is indicated for the treatment of:

• Hypertension: Used alone or in combination with other antihypertensive agents

• Benign Prostatic Hyperplasia (BPH): To relieve urinary outflow obstruction and symptoms associated with enlarged prostate in men

Mechanism of Action:

Doxazosin selectively blocks postsynaptic alpha-1 adrenergic receptors in vascular smooth muscle and the prostate. This results in:

• Vasodilation → reduces peripheral vascular resistance and blood pressure

• Relaxation of prostatic and bladder neck smooth muscle → improves urine flow and relieves BPH symptoms

Dosage and Administration:

• Hypertension: Start with 1 mg once daily; may be increased gradually based on response

• BPH: Start with 1 mg once daily; dose may be titrated

• Should be taken in the morning or evening, with or without food

• First dose may cause a sudden drop in blood pressure ("first-dose effect") — take at bedtime initially to reduce risk

Warnings and Precautions:

• Risk of postural hypotension, especially after the first dose or when increasing the dose

• Use caution in patients with liver impairment

• Can cause dizziness or fainting; caution when driving or operating machinery

• Not recommended for use in pediatric patients

Side Effects:

Common: dizziness, headache, fatigue, orthostatic hypotension, nasal congestion
Less common: palpitations, nausea, edema, dry mouth

Storage:

Store at room temperature below 30°C. Protect from moisture and light. Keep out of reach of children.