Metformin is a biguanide with an anti-hyperglycemic effect that lowers both basal and postprandial glucose and does not stimulate the insulin formation. It acts by reducing the hepatic glucose formation by preventing gluconeogenesis and glycogenolysis. It also increases sensitivity of the insulin in the muscles thus improving peripheral glucose utilization.
Indications:
• Type 2 diabetes mellitus.
• Polycystic ovary syndrome.
Points of interest:
• To reduce stomach upset, take this tablet with food or just after food.
• Tell your doctor if you experience nausea, vomiting, loss of appetite or cramps.
• Metformin has slow onset of action, it may take up to 2 weeks to establish control.