SORTIVA H 50/12.5mg 30 tab

SORTIVA H 50/12.5 mg Tablets (30 tablets)
Active Ingredients:

• Losartan Potassium 50 mg (Angiotensin II Receptor Blocker – ARB)

• Hydrochlorothiazide 12.5 mg (Thiazide Diuretic)
  Therapeutic Class: Antihypertensive combination
  Dosage Form: Oral tablet

Indications:

SORTIVA H is indicated for the treatment of:

• Essential hypertension in patients not adequately controlled with monotherapy

• May reduce the risk of stroke and other cardiovascular events by effectively lowering blood pressure

• Useful in patients requiring both a diuretic and an ARB

Mechanism of Action:

• Losartan blocks the angiotensin II receptor (AT1), leading to vasodilation, decreased aldosterone secretion, and reduced blood pressure

• Hydrochlorothiazide increases sodium and water excretion by inhibiting sodium reabsorption in the distal tubules, thereby reducing plasma volume and blood pressure

Dosage and Administration:

• Usual adult dose: One tablet once daily

• Can be taken with or without food

• Not recommended for initial treatment of hypertension; intended for patients whose blood pressure is not adequately controlled with either component alone

Warnings and Precautions:

• Contraindicated during pregnancy (especially 2nd and 3rd trimesters)

• Use with caution in patients with renal impairment, hepatic dysfunction, or electrolyte imbalance

• Monitor blood pressure, serum potassium, renal function, and electrolytes regularly

• Avoid excessive exposure to sunlight (due to risk of photosensitivity from hydrochlorothiazide)

Side Effects:

Common: dizziness, fatigue, headache, cough, increased urination
Less common: low blood pressure, electrolyte disturbances (e.g. hypokalemia), elevated uric acid or blood glucose, rash

Storage:

Store below 30°C in a dry place, protected from light. Keep out of reach of children.