CONCOR AM 5mg/10mg 30tab

 CONCOR AM 5 mg / 10 mg Tablets (30 tablets)
Active Ingredients:

• Bisoprolol Fumarate 5 mg – Beta-1 Selective Adrenergic Receptor Blocker (Beta-blocker)

• Amlodipine Besylate 10 mg – Calcium Channel Blocker (Dihydropyridine class)
  Therapeutic Class: Antihypertensive combination
  Dosage Form: Oral tablet

Indications:

CONCOR AM is indicated for the treatment of:

• Essential hypertension in patients whose blood pressure is not adequately controlled by monotherapy

• Chronic stable angina in patients requiring both beta-blocker and calcium channel blocker therapy

• Helps reduce cardiovascular risk in patients with both high blood pressure and angina

Mechanism of Action:

• Bisoprolol reduces heart rate, myocardial oxygen demand, and cardiac output by selectively blocking β1-adrenergic receptors in the heart.

• Amlodipine inhibits calcium influx in vascular smooth muscle, causing vasodilation, lowering peripheral resistance and blood pressure, and improving blood flow in angina.

Dosage and Administration:

• One tablet once daily, preferably at the same time each day

• Can be taken with or without food

• Dose adjustments should be based on the individual clinical response

• Not recommended as initial therapy

Warnings and Precautions:

• Use with caution in patients with heart failure, bradycardia, asthma, or severe hepatic impairment

• Avoid abrupt withdrawal of bisoprolol – taper gradually

• Not recommended during pregnancy or breastfeeding without physician supervision

• Monitor heart rate, blood pressure, and signs of peripheral edema

Side Effects:

Common: bradycardia, dizziness, fatigue, peripheral edema, headache, hypotension
Less common: nausea, cold extremities, sleep disturbances, palpitations, shortness of breath

Storage:

Store below 30°C, in a dry place, protected from light. Keep out of reach of children.