ALDACTONE 25MG TABS 20S

ALDACTONE 25 mg Tablets (20 tablets) Active Ingredient: Spironolactone 25 mg Therapeutic Class: Potassium-Sparing Diuretic / Aldosterone AntagonistIndications:ALDACTONE is indicated for the treatment of: Edema associated with congestive heart failure, liver cirrhosis, or nephrotic syndrome Hypertension (high blood pressure), alone or in combination with other antihypertensives Primary hyperaldosteronism (diagnosis and treatment) Hypokalemia (low potassium), especially when other diuretics cause potassium loss Heart failure (NYHA class III-IV) to reduce morbidity and mortality Mechanism of Action:Spironolactone is an aldosterone antagonist. It acts on the distal renal tubules to inhibit sodium reabsorption and potassium excretion, resulting in a diuretic effect while conserving potassium.Dosage and Administration: Edema/Hypertension: 25–100 mg daily in single or divided doses Heart failure: Typically 25 mg once daily (may be adjusted based on serum potassium) Primary hyperaldosteronism: 100–400 mg/day Dose should be individualized based on clinical condition and renal function Warnings and Precautions: Monitor serum potassium and renal function regularly Risk of hyperkalemia, especially in patients with kidney dysfunction or when combined with other potassium-sparing agents Use cautiously in elderly or diabetic patients Contraindicated in patients with anuria, acute renal insufficiency, or hyperkalemia Side Effects: Common: Hyperkalemia, gynecomastia, breast tenderness, dizziness, gastrointestinal upset Rare but serious: Severe hyperkalemia, renal dysfunction, allergic reactions Storage: Store at room temperature (below 30°C) in a dry place. Protect from moisture and light. Keep out of reach of children.